Prevalence, Seasonal variation and Feto-Maternal outcomes of Severe Pre- Eclampsia/Eclampsia at a Tertiary Hospital in North central Nigeria.

Main Article Content

Adegoriola Olubisi Ojurongbe
https://orcid.org/0009-0005-2047-3715
Matthew Olusegun Fijabiyi
https://orcid.org/0000-0001-6213-0538
Olubunmi Abidemi Tunde-Olatunji
https://orcid.org/0000-0001-6213-0538
William Taiwo
https://orcid.org/0009-0006-4072-2317
Usman Danladi Aduga
Toyin Oluwumi Fijabiyi
https://orcid.org/0000-0003-0846-2392
Adebayo Duyile Adekunle

Abstract

Background


Severe pre-eclampsia-eclampsia is a type of hypertensive disorders in pregnancy associated with increased maternal and perinatal morbidity and mortality.


Methods  


This was a retrospective study. The records of women admitted and managed with severe pre-eclampsia-eclampsia at the Federal Medical Centre Keffi  from 1st January 2020 to 31st December 2022 were retrieved from the health information management unit, labour ward, post natal ward and theatre of the hospital. Relevant data such as; patients’ age, parity, education, booking status, gestational age at delivery, diagnosis, complications, mode of delivery, birth weight, Apgar scores, month of presentation and final outcome (alive or dead) were imputed into a  proforma. The data were collated and analyzed using IBM SPSS 25. Descriptive and inferential statistics were computed for all data and results presented in simple tables and charts.


Results


There were 4,050 deliveries conducted of which 123 women had severe pre-eclampsia/eclampsia, resulting in a prevalence of 3.8%. Of these, 80 (65%) had severe pre-eclampsia and 43 (35%) had eclampsia. The mean age of the women was 29.88 ± 6.71 years and mean gestational age was 36 ± 3.483 weeks. There were 7 maternal deaths. giving a case fatality rate of 5.7%. The mean birth weight ± SD was 2.46 ± 0.860kg and stillborn rate was 26.8%. Severe pre-eclampsia/eclampsia was more common during the wet season.


Conclusions


The prevalence of pre-eclampsia/eclampsia was high in this study. with associated increased maternal and perinatal morbidity and mortality. Urgent interventions are required to address this significant health concern


 

Downloads

Download data is not yet available.

Article Details

How to Cite
1.
Prevalence, Seasonal variation and Feto-Maternal outcomes of Severe Pre- Eclampsia/Eclampsia at a Tertiary Hospital in North central Nigeria. SLJM [Internet]. 2024 Aug. 10 [cited 2024 Sep. 21];1(2):70-4. Available from: https://sljm.org/journal/index.php/sljm/article/view/49
Section
Original Article
Author Biographies

Adegoriola Olubisi Ojurongbe , Federal Medical Centre Keffi, Nasarawa State, Nasarawa State, Nigeria

Consultant Obstetrician and Gynecologist 

Matthew Olusegun Fijabiyi, Department of Obstetrics and Gynaecology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State Nigeria

Lecturer and Consultant Obstetrician and Gynecologist

Olubunmi Abidemi Tunde-Olatunji , Federal Medical Centre Keffi, Nasarawa State , Nigeria

Consultant Obstetrician and Gynecologist 

William Taiwo , The Limi Hospitals, Abuja, Federal Capital Territory, Nigeria

Consultant Obstetrician and Gynecologist 

Toyin Oluwumi Fijabiyi , Federal Medical Centre Keffi, Nasarawa State , Nigeria

Senior Registrar  in Obstetrics and Gynaecology

Adebayo Duyile Adekunle, College of Clinical Sciences, Department of Obstetrics and Gynecology Ladoke Akintola University of Technology Ogbomoso. Oyo State, Nigeria

Consultant Obstetrician and Gynecologist 

How to Cite

1.
Prevalence, Seasonal variation and Feto-Maternal outcomes of Severe Pre- Eclampsia/Eclampsia at a Tertiary Hospital in North central Nigeria. SLJM [Internet]. 2024 Aug. 10 [cited 2024 Sep. 21];1(2):70-4. Available from: https://sljm.org/journal/index.php/sljm/article/view/49

References

Kwawukume EY, Ekele BA. Hypertensive Disorders in Pregnancies .In: Comprehensive Obstetrics in the Tropics. In Kwawukume EY, Emuveyan EE, Danso KA, Ekele BA (Eds). Assemblies of God Literatures Center LTD, 2nd Edition, 2015:219-231.

Dimitriadis E, Rolnik DL, Zhou W, Estrada-Gutierrez G, Koga K. et al. Pre-eclampsia. Nature reviews disease primers. 2023;9(8):1-22. https://doi.org/10.1038/s41572-023-00417-6. DOI: https://doi.org/10.1038/s41572-023-00417-6

Onoh RC, Mamah JE, Umeokonkwo CD, Onwe EO, Ezeonu PO, Okafor L. Severe preeclampsia and eclampsia: A 6‑year review at the Federal Teaching Hospital, Abakaliki, Southeast Nigeria. Trop J Obstet Gynaecol 2019; 36:418‑23. DOI: https://doi.org/10.4103/TJOG.TJOG_45_19

Ngwenya S. Severe preeclampsia and eclampsia: Incidence, complications and perinatal outcomes at a low-resource setting, Mpilo Central Hospital, Bulawayo, Zimbabwe. Int J Women Health 2017; 9:353-7. DOI: https://doi.org/10.2147/IJWH.S131934

Hannah RT, Jennifer MS. Preeclampsia beyond pregnancy: long-term consequences for mother and child. Am J Physiol Renal Physiol 2020; 318: F1315–F1326. doi:10.1152/ajprenal.00071.2020. DOI: https://doi.org/10.1152/ajprenal.00071.2020

Narkhede AM, Karnad DR. Pre-eclampsia and related problems. Indian J Crit. Care Med. 2021;25(3): 261-266. DOI: https://doi.org/10.5005/jp-journals-10071-24032

Machano MM, Joho AA. Prevalence and risk factors associated with severe pre-eclampsia among postpartum women in Zanzibar: a cross-sectional study. Machano and Joho BMC Public Health. 2020; 20:1-10. https://doi.org/10.1186/s12889-020-09384-z DOI: https://doi.org/10.1186/s12889-020-09384-z

Ajah LO, Ozonu NC, Ezeonu PO, Lawani LO, Obuna JA, Onwe EO. The feto-maternal outcome of preeclampsia with severe features and eclampsia in Abakaliki, Southeast Nigeria. J Clin Diag Res 2016; 10:QC18-21. DOI: https://doi.org/10.7860/JCDR/2016/21078.8499

Awoyesuku PA, John DH, Lebara LB. Maternal and perinatal outcome in severe preeclampsia and eclampsia at the rivers state university teaching hospital, Nigeria. Int J Reprod Contracept Obstet Gynecol 2020; 9:4382-8. DOI: https://doi.org/10.18203/2320-1770.ijrcog20204784

Chuppana R, Madhavi AP, Sharon PS, Priya SS, Shehnaz S. A study of maternal deaths from preeclampsia and eclampsia in a tertiary care centre. IAIM 2018; 5:6-10.

Tebeu P, Halle G, Ngowa JD, Domgue JF, Ourtching C, Mboudou E. Outcome of pregnancy in preeclampsia at the regional hospital Maroua- Cameroon. Int J Reprod Med Gynecol 2017; 3:34-9.

Awoyesuku PA, MacPepple DA, Altraide BO. Magnitude and Trends in Maternal Mortality and Causative factors: A 7-year review at a tertiary hospital in Port Harcourt, Nigeria. J Adv Med Res. 2020;32(1):103-9. DOI: https://doi.org/10.9734/jammr/2020/v32i130357

WHO. Prevention and treatment of pre-eclampsia and eclampsia. 2011.

Frank IO, Michael JM, Jenny R, Joseph O. Prevalence and risk factors for preeclampsia/eclampsia in Northern Tanzania. J Public Heal Epidemiol. 2020; 12(2):78–85. DOI: https://doi.org/10.5897/JPHE2019.1143

Mooij R, Lugumila J, Mwashambwa MY, Mwampagatwa IH, Dillen J Van. Characteristics and outcomes of patients with eclampsia and severe preeclampsia in a rural hospital in Western Tanzania: a retrospective medical record study. 2015;1–7. DOI: https://doi.org/10.1186/s12884-015-0649-2

Oladapo O, Adetoro O, Ekele B, Chama C, Etuk S, Aboyeji A, et al. When getting there is not enough: A cross-sectional study of 998 maternal deaths and 1451 near misses in public tertiary hospitals in a low-income country. BJOG, 2015. Available from: www.doi. org/10.1111/1471-0528.13450. DOI: https://doi.org/10.1111/1471-0528.13450

Akaba GO, Anyang UI, Ekele BA. Prevalence and materno-fetal outcomes of preeclampsia/eclampsia amongst pregnant at a teaching hospital in north –central Nigeria: a retrospective cross-sectional study. Clin Hypertens.2021; 27(1):20. doi: 10.1186/s40885-021-00178-y. DOI: https://doi.org/10.1186/s40885-021-00178-y

Wagnew M, Muluken D, Worku A, Nyagero J. Trends of preeclampsia/eclampsia and maternal and neonatal outcomes among women delivering in Addis ababa selected government hospitals, Ethiopia: A retrospective cross-sectional study. Pan Afr Med J 2016; 25:12-8.

Akinola OI, Fabanwa AO, Gbagesin A, Ottun TA, Kusemiju OA. Improving the clinical outcome in cases of eclampsia: the experience at Lagos State university teaching hospital, Ikeja. Int J Third World Med. 2008; 6(2):2. DOI: https://doi.org/10.5580/2ad

Airede LR, Ekele BA. Adolescent maternal mortality in Sokoto, Nigeria. J Obstet. Gynaecol. 2003;23(2):163-5. DOI: https://doi.org/10.1080/0144361031000074709

Duley L. Pre-eclampsia and the hypertensive disorders of pregnancy. Br Med Bull. 2003; 67:16176. DOI: https://doi.org/10.1093/bmb/ldg005

Okogbenin SA, Eigbefoh JO, Omorogbe F, Okonta PI, Ohihoin AG. Eclampsia in Irrua specialist teaching hospital: a five-year review. Niger J Clin Pract. 2010;13(2):149-53.

Abate MM, Lakew Z. Eclampsia: A 5-year retrospective review of 216 cases managed in 2 teaching hospitals in Addis Ababa. Ethiop Med J. 2006; 44(1):27-31.

Okafor UV, Ezegwu HU. Cesarean delivery in preeclampsia and seasonal variation in a tropical rainforest belt. J Postgrad Med. 2010; 56:21-3. doi:10.4103/0022-3859.62431. DOI: https://doi.org/10.4103/0022-3859.62431

Ikeanyi ME, Abasi JI. Seasonal variation in the incidence of preeclampsia- eclampsia in Bayelsa state in the Niger Delta Region of Nigeria. Indian Journal of Obstetrics and Gynecology Research 2020; 7(2):157–162. DOI: https://doi.org/10.18231/j.ijogr.2020.033

Agobe JT, Good W, Hancock KW. Meteorological relations of eclampsia in Lagos, Nigeria. Br J Obstet Gynaecol. 1981; 88(7):706-710. DOI: https://doi.org/10.1111/j.1471-0528.1981.tb01269.x

Onwuhafua PI, Onwuhafua A, Adze J, Mairami Z. Eclampsia in Kaduna State of Nigeria. A proposal for better outcome. Niger J Med. 2001; 10(2):81-84.

Similar Articles

You may also start an advanced similarity search for this article.